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Benign symmetric lipomatosis, also known as Madelung's disease, is an adult-onset skin condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area. [1] The symmetrical fat deposits are made of unencapsulated lipomas , which distinguishes it from typical lipomatosis which has encapsulated lipomas that ...
Lipomas are normally removed by simple excision. [27] The removal can often be done under local anesthetic and takes less than 30 minutes. This cures the great majority of cases, with about 1–2% of lipomas recurring after excision. [28] Liposuction is another option if the lipoma is soft and has a small connective tissue component.
Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1] In 1993, a genetic polymorphism within lipomas was localized to chromosome 12q15 , where the HMGIC gene encodes the high-mobility-group protein isoform I-C. [ 2 ] This is one of the most commonly found mutations in solitary ...
Adenolipomas are diagnosed by surgical resection and examining the tumor with a microscope. [5] The presence of eccrine sweat glands are used to distinguish the tumor from a common lipoma . Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis.
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Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. [3] Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. [4]
The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2] Familial Multiple Lipomatosis can be identified when multiple lipomas occur in multiple family members that span different generations. [2] Some people may have hundreds of lipomas ...