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The ampulla of Vater, hepatopancreatic ampulla or hepatopancreatic duct is the common duct that is usually formed by a union of the common bile duct and the pancreatic duct within the wall of the duodenum. This common duct usually features a dilation ("ampulla").
The sphincter regulates the secretion of pancreatic juice and bile into the duodenum. [3] It also prevents reflux of duodenal contents into the ampulla of Vater. [4] By preventing reflux of the contents of the duodenum, the sphincter of Oddi prevents the accumulation of particulate matter and sludge in the bile ducts, reducing the risk of cholangitis.
The path is as follows: bile canaliculi → canals of Hering → interlobular bile ducts → intrahepatic bile ducts → left and right hepatic ducts merge to form → common hepatic duct exits liver and joins → cystic duct (from gall bladder) forming → common bile duct → joins with pancreatic duct → forming ampulla of Vater → enters ...
The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. There are many anatomical variants reported, but these are quite rare.
Functional disorders of the gallbladder, bile duct and pancreas have been defined and classified by the Rome criteria for functional gastrointestinal disorders. [2] The criteria outline three variants of functional disorders of the gallbladder, bile duct and pancreas, termed functional gallbladder disorder, functional biliary sphincter of Oddi disorder and functional pancreatic sphincter of ...
It appears rounded and is often covered by a fold on the uppermost side of the papilla; that is, the side which receives contents from the stomach. [4] The major duodenal papilla is seen from the duodenum as lying within a mucosal fold. The minor duodenal papilla is situated 2 cm proximal. [2]
Vater is primarily known for his work in anatomy, but he also published works in the fields of chemistry, botany, pharmacology and gynaecology. He was the first to describe the hepatopancreatic ampulla , which is the juncture of the pancreatic duct and the common bile duct , and is now referred to as the ampulla of Vater .
The ampulla pulla of vas deferens, also called the ampulla pulla of ductus deferens, is an enlargement of the vas deferens at the pulla fundus of the bladder which acts as a reservoir for sperm. This structure is seen in some mammalian and squamate species and is sometimes tortuous in shape.