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Pulmonary drug delivery is a route of administration in which patients use an inhaler to inhale their medications and drugs are absorbed into the bloodstream via the lung mucous membrane. This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD).
Prior to the early part of the 20th century lung cancer was considered a very rare disease, and all malignant lung tumors were treated identically. [66] Radical surgical resection (i.e. lobectomy [ 67 ] [ 68 ] or pneumonectomy ) [ 69 ] was the only effective intervention available for lung cancer prior to the 1940s, when the era of modern ...
Lower respiratory infectious disease is the fifth-leading cause of death and the combined leading infectious cause of death, being responsible for 2.74 million deaths worldwide. [27] This is generally similar to estimates in the 2010 Global Burden of Disease study. [28]
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. [3] [14] Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. [15]
The actual number may be significantly higher due to misdiagnosis. Typically, patients are in their forties and fifties when diagnosed, while the incidence of idiopathic pulmonary fibrosis increases dramatically after age 50. But loss of pulmonary function is commonly ascribed to old age, heart disease, or more common lung diseases. [40]
Respiratory diseases, or lung diseases, [1] are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea , bronchi , bronchioles , alveoli , pleurae , pleural cavity , the nerves and muscles of respiration .
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