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Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus. Most cases of endometrial hyperplasia result from high levels of estrogens , combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this ...
Atypical endometrial hyperplasia may represent an early neoplastic process which can lead to endometrial adenocarcinoma. [20] The development of endometrial adenocarcinoma from endometrial hyperplasia is a typical example of how the effects of pathologic hyperplasia can lead to neoplasia, and females who exhibit hyperplasia of the endometrium ...
Uterine hyperplasia, or enlarged uterus, is a medical symptom in which the volume and size of the uterus in a female is abnormally high. It can be a symptom of medical conditions such as adenomyosis , uterine fibroids , ovarian cysts , and endometrial cancer .
Endometrial cancer is the most common form of cancer of the female reproductive organs in the U.S., with 67,880 new cases diagnosed each year.Over the past decades, rates have increased and ...
Metropathia haemorrhagica, also known as metropathia haemorrhagica cystica, is a menstrual disorder which is defined as a specialized type of anovulatory dysfunctional uterine bleeding associated with endometrial hyperplasia and intermenstrual bleeding.
(E): endometrial atypical hyperplasia (Left: HE × 10) and endometrial atypical cells (Right: HE × 200) (F) endometrial carcinoma (Left: HE × 400) and endometrial cancer cells (Right: HE × 400). Chorionic tissue can result in marked endometrial changes, known as an Arias-Stella reaction, that have an appearance similar to cancer. [15]
The endometrial surface is at the top of the image, and the serosa is at the bottom. Misplaced endometrial tissue proliferation in the myometrium causes symptoms through different mechanisms. [6] Uterine menstrual contractions are caused by prostaglandin, which is produced by normal endometrial tissue. [6]
Endometrial polyps can be detected by vaginal ultrasound (sonohysterography), hysteroscopy and dilation and curettage. [3] Detection by ultrasonography can be difficult, particularly when there is endometrial hyperplasia (excessive thickening of the endometrium). [2] Larger polyps may be missed by curettage. [10]