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Lifitegrast, sold under the brand name Xiidra (/ ˈ z aɪ d r ə / [2]), is a medication for the treatment of signs and symptoms of dry eye, a syndrome called keratoconjunctivitis sicca. Lifitegrast reduces inflammation by inhibiting inflammatory cell binding. [ 3 ]
Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system. [2] [6] Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly. [2]
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
drops GSL General sales list Gutt/g Guttae (drops) Meds Medications Nocte/QHS At night Occ Ointment od/QD Once a day otc Over the counter (bought medication) P Pharmacy (drug) POM Prescription-only medicine prn When required q Every (e.g. q2h – every two hours) qds/qid Four times a day Rx Prescription tds/tid Three times a day ung Ointment
Persons with dry eye conditions can be fitted with punctal plugs that seal the ducts to limit the amount of fluid drainage and retain moisture. During an ear infection, excess mucus may drain through the nasolacrimal duct in the opposite way tears drain. [citation needed] In humans, the tear ducts in males tend to be larger than the ones in ...
When applied to the surface of the eye, side effects may include a brief period of blurry vision and discoloration of contact lenses of the soft type. [7] [3] When used by mouth or injection, side effects may include headache, nausea, and a change to the color of the skin for a brief period of time. [3] Allergic reactions may rarely occur. [3]
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