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Considering the immense importance of the non-canonical base pairs in RNA structure, folding and functions, researchers from multiple domains – biology, chemistry, physics, mathematics, computer science, etc., have joined in the effort to understand their structure, dynamics, function and their consequences.
Gene conversion is the process by which one DNA sequence replaces a homologous sequence such that the sequences become identical after the conversion. [1] Gene conversion can be either allelic, meaning that one allele of the same gene replaces another allele, or ectopic, meaning that one paralogous DNA sequence converts another.
The primary goal of the technique is to determine the root cause of a defect or problem by repeating the question "why?" five times, each time directing the current "why" to the answer of the previous "why". The method asserts that the answer to the fifth "why" asked in this manner should reveal the root cause of the problem. [2]
A diagram of DNA base pairing, demonstrating the basis for Chargaff's rules. Chargaff's rules (given by Erwin Chargaff) state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine.
The larger nucleobases, adenine and guanine, are members of a class of doubly ringed chemical structures called purines; the smaller nucleobases, cytosine and thymine (and uracil), are members of a class of singly ringed chemical structures called pyrimidines. Purines are only complementary with pyrimidines: pyrimidine-pyrimidine pairings are ...
In mathematics, a dual system, dual pair or a duality over a field is a triple (,,) consisting of two vector spaces, and , over and a non-degenerate bilinear map:.. In mathematics, duality is the study of dual systems and is important in functional analysis.
A pairing is called perfect if the above map is an isomorphism of R-modules and the other evaluation map ′: (,) is an isomorphism also. In nice cases, it suffices that just one of these be an isomorphism, e.g. when R is a field, M,N are finite dimensional vector spaces and L=R .
It commemorates the Theory of Superconductivity developed here by John Bardeen and his students, for which they won a Nobel Prize for Physics in 1972. Microscopic theory of superconductivity In physics , the Bardeen–Cooper–Schrieffer ( BCS ) theory (named after John Bardeen , Leon Cooper , and John Robert Schrieffer ) is the first ...