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Colchicine is taken by mouth. [11] The injectable route of administration for colchicine can be toxic. In 2008, the US Food and Drug Administration removed all injectable colchicine from the US market. [12] [13] Colchicine has a narrow therapeutic index, so overdosing is a significant risk.
It should be considered in all patients with acute pericarditis, preferably in combination with a short-course of NSAIDs. [10] For patients with a first episode of acute idiopathic or viral pericarditis, they should be treated with an NSAID plus colchicine 1–2 mg on first day followed by 0.5 daily or twice daily for three months.
Colchicine (Colcrys) for pericarditis: colchicine is indicated for the treatment and prevention of gout, though it is also generally considered first-line treatment for acute pericarditis, as well as preventing recurrent episodes. Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis ...
Colchicine. Limited research has shown that the anti-inflammatory drug colchicine may help stabilize Peyronie’s disease when combined with vitamin E in the early stages of the disease. The best ...
Generally abbreviated to "P.R.N." or "PRN", pro re nata refers to the administration of prescribed medication whose timing is left to the patient (in the case of patient-controlled analgesia), nurse, or caregiver, as opposed to medication that is taken according to a fixed (primarily daily) schedule (a.k.a. "scheduled dosage").
Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...
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