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The prefrontal cortex. Hypofrontality is a state of decreased cerebral blood flow (CBF) in the prefrontal cortex of the brain. Hypofrontality is symptomatic of several neurological medical conditions, such as schizophrenia, attention deficit hyperactivity disorder (ADHD), bipolar disorder, and major depressive disorder.
Frontal lobe disorder, also frontal lobe syndrome, is an impairment of the frontal lobe of the brain due to disease or frontal lobe injury. [5] The frontal lobe plays a key role in executive functions such as motivation, planning, social behaviour, and speech production.
The symptoms observed in bvFTD are caused by dysfunction of the orbitofrontal cortex; thus these two neuropsychological tests might be useful in detecting early-stage bvFTD. However, as self-monitoring and somatic marker processes are so complex, it likely involves other brain regions.
In psychology and neuroscience, executive dysfunction, or executive function deficit is a disruption to the efficacy of the executive functions, which is a group of cognitive processes that regulate, control, and manage other cognitive processes. [1] Executive dysfunction can refer to both neurocognitive deficits and behavioural symptoms.
Dysexecutive syndrome (DES) consists of a group of symptoms, [1] usually resulting from brain damage, that fall into cognitive, behavioural and emotional categories and tend to occur together. The term was introduced by Alan Baddeley [ 2 ] [ 3 ] to describe a common pattern of dysfunction in executive functions , such as planning, abstract ...
The Wisconsin Card Sorting Test (WCST) can be used in conjunction with other tests to speculate to possible dysfunction of the prefrontal cortex, the front-most area of the frontal lobe, that plays an important role in executive functioning. However, since the age of modern medicine and brain imaging, the WCST has been purported to be ...
Neuroimaging and postmortem studies have identified abnormalities in several brain regions, with the ventral prefrontal cortex and amygdala being most frequently implicated. Dysfunction within the emotional circuits of these regions has been hypothesized as a potential mechanism underlying bipolar disorder. [ 2 ]
The anterior superior frontal lobe is known as the prefrontal cortex which is responsible for the initiation and ideation of verbal speech. [7] The damage leaves the major language networks, Broca's and Wernicke’s areas and the arcuate fasiculus , unaffected. [ 1 ]