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Parvovirus infection in pregnant women is associated with hydrops fetalis due to severe fetal anemia, sometimes leading to miscarriage or stillbirth. [ 33 ] [ 46 ] This is due to a combination of hemolysis of the red blood cells, as well as the virus directly negatively affecting the red blood cell precursors in the bone marrow.
Exposure to parvovirus B19 typically does not impact a pregnancy, but in some cases, the infection can cross the placenta and infect the fetus, says Schaffner. This can lead to adverse effects ...
The CDC issued an alert over rising human parvovirus B-19 cases, also known as "fifth disease" and "slapped-check disease." Most cases of parvovirus are mild, but pregnant and immunocompromised ...
Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, [3] is a common and contagious disease caused by infection with parvovirus B19. [4] This virus was discovered in 1975 and can cause other diseases besides fifth disease. [5]
Parvovirus B19 is highly infectious. Half of the people exposed in one household can become infected, the CDC said. Similar numbers are seen at schools among students and staff during outbreaks.
B19 infection is often asymptomatic but can manifest in a variety of ways, including Fifth disease with its characteristic rash in children, persistent anemia in immunocompromised persons and in people who have underlying hemoglobinopathies, [20] transient aplastic crises, hydrops fetalis in pregnant women, and arthropathy. Human bocavirus 1 is ...
Parvovirus B19 can also spread through blood or blood products, though infection through transfusion is rare. In addition, pregnant people who are infected can spread the virus to their unborn child.
An infection that often goes unrecognized in people with AIDS is Parvovirus B19. Its main consequence is anemia , which is difficult to distinguish from the effects of antiretroviral drugs used to treat AIDS itself.