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These T cells may be activated by the Hu proteins. [13] [14] In people with cancer, the cancer has a likely role in the cause of the encephalitis. In a paraneoplastic syndrome, a cancer cell can create proteins that are normally only found as naturally occurring proteins in other cell types in other parts of the body.
The temporal lobe epileptiform discharge is a pattern seen on the electroencephalgram (EEG) test; temporal lobe epileptiform discharges occur between seizures and confirm the diagnosis of temporal lobe epilepsy. [3] Long-term video-EEG monitoring may record the behavior and EEG during a seizure. [3]
Antipsychotics cause an increased calcium release from the sarcoplasmic reticulum of muscle cells which can result in rigidity and eventual cell breakdown. No major studies have reported an explanation for the abnormal EEG , but it is likely also attributable to dopamine blockage leading to changes in neuronal pathways.
The EEG has been used for many purposes besides the conventional uses of clinical diagnosis and conventional cognitive neuroscience. An early use was during World War II by the U.S. Army Air Corps to screen out pilots in danger of having seizures; [116] long-term EEG recordings in epilepsy patients are still used today for seizure prediction.
A paper published in 2023 showed that burst suppression and epilepsy may share the same ephaptic coupling mechanism. [6] When inhibitory control is sufficiently low, as in the case of certain general anesthetics such as sevoflurane (due to a decrease in the firing of interneurons [7]), electric fields are able to recruit neighboring cells to fire synchronously, in a burst suppression pattern.
In testing narcotic antagonists (naloxone, cyclazocine) and opioid substitutes (methadone, levomethadyl) in the treatment of opioid dependence, the quantitative EEG experiments showed the efficiency of antagonistic and replacement activity of different dosing schedules. Dose finding trials of naloxone showed no specific CNS effect when ...
Epilepsy, a brain disorder that causes seizures, is one of the most common conditions that affects the brain. According to the Centers for Disease Control and Prevention (CDC), about 3.4 million ...
Diagnosis of PME is based on the individual's signs and symptoms as well as failure to respond to antiepileptic drugs and therapy. [3] Further diagnosis support includes EEG results, genetic testing, enzyme testing, and skin and muscle biopsies. [2] Gaucher's disease can be diagnosed through enzyme testing as it is a metabolic disease. [4]