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Michael Patrick Sheetz was a cell biologist, a pioneer of mechanobiology and biomechanics, and a key contributor to the discovery of kinesin. He served as the Robert A. Welch Distinguished University Chair in Chemistry at the University of Texas Medical Branch , Galveston , the department of biochemistry and molecular biology.
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He then heard of the research of Michael Sheetz and James Spudich, who used a video camera on a microscope to film myosin-coated beads moving along actin filaments. In 1983, Vale and Sheetz decided to test whether the movement of myosin on actin was the source for organelle transport in axons, using the squid giant axon as a model.
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