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Bacteremia can travel through the blood stream to distant sites in the body and cause infection (hematogenous spread). Hematogenous spread of bacteria is part of the pathophysiology of certain infections of the heart ( endocarditis ), structures around the brain ( meningitis ), and tuberculosis of the spine ( Pott's disease ).
Diastolic blood pressure falls during the early stages of sepsis, causing a widening/increasing of pulse pressure, which is the difference between the systolic and diastolic blood pressures. If sepsis becomes severe and hemodynamic compromise advances, the systolic pressure also decreases, causing a narrowing/decreasing of pulse pressure. [ 23 ]
Blood is normally sterile. [1] The presence of bacteria in the blood is termed bacteremia, and the presence of fungi is called fungemia. [2] Minor damage to the skin [3] or mucous membranes, which can occur in situations like toothbrushing or defecation, [4] [5] can introduce bacteria into the bloodstream, but this bacteremia is normally transient and is rarely detected in cultures because the ...
Infective endocarditis is an infection of the inner surface of the heart (endocardium), usually the valves. [1] Signs and symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count.
[3] [44] Once the bacteria have entered the bloodstream, they can infect various organs, causing infective endocarditis, septic arthritis, and osteomyelitis. [44] This disease is particularly prevalent and severe in the very young and very old. [3] Without antibiotic treatment, S. aureus bacteremia has a case fatality rate around 80%. [3]
These early findings may be followed by signs and symptoms of shock. [ citation needed ] Biliary tract infection is usually caused by E. coli, Klebsiella and Enterococcus spp. Anaerobes (mostly B. fragilis group, and rarely C. perfringens ) can be recovered in complicated infections associated with carcinoma, recurrent infection, obstruction ...
Bacterial Infections If a bacterial infection goes untreated for too long, it can make you really sick. Often, this results in a fever, but chills sans fever have been reported in people with a ...
S. aureus is also implicated [6] in toxic shock syndrome; during the 1980s some tampons allowed the rapid growth of S. aureus, which released toxins that were absorbed into the bloodstream. Any S. aureus infection can cause the staphylococcal scalded skin syndrome , a cutaneous reaction to exotoxin absorbed into the bloodstream.