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If a patient's protein level is very low there could be a possibility that the patient may have a liver or kidney disease since globulins are produced in the liver. There are two different types of blood tests. There is the total protein test or the serum protein electrophoresis which measures the level of each protein in a patient's blood.
Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. [1] The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma , a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy ...
Serum total protein, also known as total protein, is a clinical chemistry parameter representing the concentration of protein in serum. [1] Serum contains many proteins including serum albumin, a variety of globulins, and many others. While it is possible to analyze these proteins individually, total protein is a relatively quick and ...
Researchers have identified protein signatures in blood tests that can be used to detect or predict up to 67 diseases, using UK Biobank data in a cohort of nearly 42,000 participants.
A macroglobulin is a plasma globulin of high molecular weight. [1] Elevated levels of macroglobulins ( macroglobulinemia ) may cause manifestations of excess blood viscosity (as is the case for IgM antibodies in Waldenström macroglobulinemia ) and/or precipitate within blood vessels when temperature drops (as in cryoglobulinaemia ).
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
The direct Coombs test is used to detect antibodies or complement proteins attached to the surface of red blood cells. To perform the test, a blood sample is taken and the red blood cells are washed (removing the patient's plasma and unbound antibodies from the red blood cells) and then incubated with anti-human globulin ("Coombs reagent").
By analyzing a large database of human tissue samples, they found that muscle cells contain high levels of a protein called BCL6, suggesting it may also play a significant role in regulating ...