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Interstitial cystitis (IC), a type of bladder pain syndrome (BPS), is chronic pain in the bladder and pelvic floor of unknown cause. [1] Symptoms include feeling the need to urinate right away , needing to urinate often , and pain with sex . [ 1 ]
In relation to interstitial cystitis, when noxious stimuli are present, it causes injury to the bladder mucosa resulting in recruitment of inflammatory cells. [3] Disruption of glycosaminoglycan (GAG) layer [ 14 ] along with the increased presence of mast cells , T cells , and B cells causes the bladder epithelium to become more permeable.
Interstitial cystitis (IC), a type of bladder pain syndrome (BPS), is chronic pain in the bladder and pelvic floor of unknown cause. [1] It is the urologic chronic pelvic pain syndrome of women. [2] Symptoms include feeling the need to urinate right away, needing to urinate often, and pain with sex. [1]
Patients with interstitial cystitis may find relief by modifying their diet to remove foods and beverages that trigger symptoms: caffeinated beverages, particularly coffee (regular and decaf), tea, green tea, soda, artificial sugars and fruit juices. Cranberry juice may also trigger intense pain and discomfort.
Feline idiopathic cystitis begins as an acute non-obstructive episode and is self-limiting in about 85% of cases, resolving itself in a week. In approximately 15% of cases, it can escalate into an obstructive episode ("blocked cat") which can be life-threatening for a male cat. [5]
Urologic chronic pelvic pain syndrome (UCPPS) is ongoing bladder pain in either sex, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men and interstitial cystitis [1] [2] [3] or painful bladder syndrome (IC/PBS) in women. [4] [5] It was coined as an umbrella term for use in research into urologic pain syndromes in men and women.
O'Leary is named for the O'Leary-Sant Interstitial Cystitis Symptom Index, for measuring lower urinary tract symptoms and their impact in people with interstitial cystitis. [13] It looks at four main symptoms of interstitial cystitis and bladder pain syndrome; bladder pain, urgency, and frequency.
Interstitial cystitis was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake.