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Ground-glass opacity (GGO) is a finding seen on chest x-ray (radiograph) or computed tomography (CT) imaging of the lungs. It is typically defined as an area of hazy opacification (x-ray) or increased attenuation (CT) due to air displacement by fluid, airway collapse, fibrosis , or a neoplastic process . [ 1 ]
Sarcoidosis is a disease of unknown cause characterized by non-necrotizing ("non-caseating") granulomas in multiple organs and body sites, [12] most commonly the lungs and lymph nodes within the chest cavity. Other common sites of involvement include the liver, spleen, skin, and eyes.
A posterior-anterior (PA) chest X-ray is the standard view used; other views (lateral or lordotic) or CT scans may be necessary. [citation needed] In active pulmonary TB, infiltrates or consolidations and/or cavities are often seen in the upper lungs with or without mediastinal or hilar lymphadenopathy. [1] However, lesions may appear anywhere ...
The diagnosis is usually suspected following a CT scan. Typical features on CT include solid and sub-solid nodules, ground glass change and reticulation. [7] There may be features of multi-system involvement such as adenopathy and splenomegaly. [citation needed] The commonest abnormality on lung function testing is a decrease in gas transfer. [2]
One or more lung nodules can be an incidental finding found in up to 0.2% of chest X-rays [3] and around 1% of CT scans. [ 4 ] The nodule most commonly represents a benign tumor such as a granuloma or hamartoma , but in around 20% of cases it represents a malignant cancer , [ 4 ] especially in older adults and smokers .
It is a small area of granulomatous inflammation, only detectable by chest X-ray if it calcifies or grows substantially (see tuberculosis radiology). [2] Typically these will heal, but in some cases, especially in immunosuppressed patients, it will progress to miliary tuberculosis (so named due to the granulomas resembling millet seeds on a ...
To exclude sarcoidosis in a case presenting with pulmonary symptoms might involve a chest radiograph, CT scan of chest, PET scan, CT-guided biopsy, mediastinoscopy, open lung biopsy, bronchoscopy with biopsy, endobronchial ultrasound, and endoscopic ultrasound with fine-needle aspiration of mediastinal lymph nodes (EBUS FNA).
Contrasted CT scans of the chest are usually used to confirm diagnosis of for lung cancer and abscesses, as well as to assess lymph node status at the hila and the mediastinum. CT pulmonary angiogram , which uses time-matched ("phased") protocols to assess the lung perfusion and the patency of great arteries and veins , particularly to look for ...
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