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  2. Muscle fatigue - Wikipedia

    en.wikipedia.org/wiki/Muscle_fatigue

    Muscle fatigue is not the same as muscle weakness, though weakness is an initial symptom. Despite a normal amount of force being generated at the start of activity, once muscle fatigue has set in and progressively worsens, if the individual persists in the exercise they will eventually lose their hand grip, or become unable to lift or push with ...

  3. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    It was once believed that lactic acid build-up was the cause of muscle fatigue. [14] The assumption was lactic acid had a "pickling" effect on muscles, inhibiting their ability to contract. The impact of lactic acid on performance is now uncertain, it may assist or hinder muscle fatigue. [citation needed]

  4. Why You Feel That Burning Sensation in Your Legs During Hard ...

    www.aol.com/why-feel-burning-sensation-legs...

    “Traditional models of muscle fatigue considered lactate as a metabolic waste product and a limitation in endurance exercise performance,” says Casadio. “But lactate in the blood is actually ...

  5. Lactate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Lactate_dehydrogenase

    The onset of acidosis during periods of intense exercise is commonly attributed to accumulation of hydrogens that are dissociated from lactate. Previously, lactic acid was thought to cause fatigue. From this reasoning, the idea of lactate production being a primary cause of muscle fatigue during exercise was widely adopted.

  6. Fatigue - Wikipedia

    en.wikipedia.org/wiki/Fatigue

    Physical fatigue, or muscle fatigue, is the temporary physical inability of muscles to perform optimally. The onset of muscle fatigue during physical activity is gradual, and depends upon an individual's level of physical fitness – other factors include sleep deprivation and overall health. [131]

  7. Metabolic myopathy - Wikipedia

    en.wikipedia.org/wiki/Metabolic_myopathy

    Abnormal muscle fatigue (premature fatigue and/or inability to get into second wind), muscle pain (myalgia), cramping or muscle stiffness during and/or after exercise, [citation needed] Shortness of breath , or rapid breathing , or heavy breathing , or both (exercise hyperventilation) [citation needed]

  8. Central nervous system fatigue - Wikipedia

    en.wikipedia.org/wiki/Central_Nervous_System_Fatigue

    Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.

  9. Bioenergetic systems - Wikipedia

    en.wikipedia.org/wiki/Bioenergetic_systems

    When H + ions accumulate in the muscles causing the blood pH level to reach low levels, temporary muscle fatigue results. Another limitation of the lactic acid system that relates to its anaerobic quality is that only a few moles of ATP can be resynthesized from the breakdown of sugar.

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