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In the United States, progestogen-only pills are available in 350-μg Norethisterone, 4-mg Drospirenone and Norgestrel 0.075-mg formulations. [18] Norgestrel is FDA-approved for over-the-counter availability, [19] and Norethindrone and Drospirenone are available by prescription.
A pharmacist who counsels for a prescription drug can view a patient's profile, which includes their current list of concurrent medications and allergies to medications. However, an OTC counseling session may occur in the aisle of the store, forcing pharmacists to elicit the necessary information from patients directly. [6]
Due to its weak androgenic activity, norethisterone can produce androgenic side effects such as acne, hirsutism, and voice changes of slight severity in some women at high dosages (e.g., 10 to 40 mg/day). [17] This is notably not the case with combined oral contraceptives that contain norethisterone and EE, however. [18]
The contraceptive efficacy of norgestrel was established in the U.S. with the original approval for prescription use in 1973. [2] In July 2023, the FDA approved norgestrel for over-the-counter sale. [2] [27] The FDA granted the approval to Laboratoire HRA Pharma which was acquired by Perrigo Company plc. [2]
Arizona is the latest state to enable pharmacists to prescribe birth control. Since 2016, 29 states and Washington, D.C. have passed such laws. Where you can get birth control from a pharmacist ...
Norethisterone and ethinylestradiol levels over 24 hours after a single oral dose of 10 mg NETA in postmenopausal women. [25] NETA metabolizes into ethinylestradiol at a rate of 0.20 to 0.33% across a dose range of 10 to 40 mg. [26] [27] Peak levels of ethinylestradiol with a 10, 20, or 40 mg dose of NETA were 58, 178, and 231 pg/mL, respectively.