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Chromium(III) picolinate (also trivalent chromium) is a chemical compound with the formula Cr(C 5 H 4 N(CO 2)) 3, commonly abbreviated as CrPic 3. It is a bright-red coordination compound derived from chromium (III) and picolinic acid .
Trivalent chromium, or chromium(III), is an essential trace mineral in the human diet. [3] In some nutritional supplements, chromium(III) occurs as chromium(III) picolinate (in which chromium is bound to picolinic acid) or chromium(III) nicotinate (in which chromium is bound to nicotinic acid). Nicotinic acid is also known as the B vitamin niacin.
This NOW Foods Chromium Picolinate contains 200 mcg of chromium per dose and it’s gluten-free, dairy-free, and non-GMO. The product has also been third-party tested for quality and potency which ...
Dietary supplements containing chromium are widely available in the United States, with claims for benefits for fasting plasma glucose, hemoglobin A1C and weight loss. Reviews report the changes as modest, and without scientific consensus that the changes have a clinically relevant impact.
They reported an average decrease in HbA1c (A1C) of almost 2 percentage points after only four months of treatment with 1,000 μg chromium daily. Since then, the effects of chromium on glycemic control, lipid profile, weight, and muscular strength have been investigated, both in nondiabetic healthy subjects and in patients with type 2 diabetes.
Structure of Zn(picolinate) 2 (H 2 O) 2. Hydrogenation of picolinic acid gives piperidine-2-carboxylic acid, a precursor to the drug Mepivacaine. Picolinic acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. [5] [6] It is a substrate in the Mitsunobu reaction.
A 2003 pilot trial of 15 patients suggested that chromium picolinate might have antidepressant effects in atypical depression.[15] A larger trial in 2005 set up to test this finding found no effect on depression in its test group, but suggested that the use of chromium supplementation could help to reduce carbohydrate cravings and regulate ...
Metal toxicity or metal poisoning is the toxic effect of certain metals in certain forms and doses on life.Some metals are toxic when they form poisonous soluble compounds. . Certain metals have no biological role, i.e. are not essential minerals, or are toxic when in a certain for