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Zolpidem is a nonbenzodiazepine, or Z-drug, which acts as a sedative and hypnotic [11] [20] as a positive allosteric modulator at the GABA A receptor. It is an imidazopyridine and increases GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [11]
Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1]
Benzodiazepines work by increasing the effects of a neurotransmitter called gamma-amino butyric acid, or GABA. GABA is an inhibitory neurotransmitter — its job is to decrease activity in the ...
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system, via modulating GABA A receptors similarly to the way benzodiazepine drugs do inducing sedation but not with the anti-anxiety properties of the benzodiazepines. Zopiclone is a sedative. It works by causing a ...
Before adding any new supplement or sleep aid to your nighttime routine, speak with your healthcare provider to make sure it’s safe and appropriate for you. Meeko Media/Istockphoto 6.