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Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing , leg or feet swelling, and fatigue. [1] ADHF is a common and potentially serious cause of acute respiratory distress. The condition is caused by severe congestion of multiple organs by fluid ...
The related medication eplerenone was shown in the EPHESUS trial [31] to have a similar effect, and it is specifically labelled for use in decompensated heart failure complicating acute myocardial infarction. While the antagonism of aldosterone will decrease the effects of sodium and water retention, it is thought that the main mechanism of ...
Heart failure - Giving 2.5 times of previous oral dose twice daily for those with acute decompensated heart failure is a reasonable strategy. However, daily assessment of clinical response is needed to adjust the subsequent doses. [6] Edema - Volume overload associated with liver cirrhosis, heart failure, or nephrotic syndrome [11]
For example, cardiac decompensation may refer to the failure of the heart to maintain adequate blood circulation, after long-standing (previously compensated) vascular disease (see heart failure). Short-term treatment of cardiac decompensation can be achieved through administration of dobutamine , resulting in an increase in heart contractility ...
Acute decompensated heart failure is a worsening of chronic heart failure symptoms, which can result in acute respiratory distress. [66] High-output heart failure can occur when there is increased cardiac demand that results in increased left ventricular diastolic pressure which can develop into pulmonary congestion (pulmonary edema).
It was shown that kidney failure complicates one-third of all admissions for heart failure, which is the leading cause of hospitalization in the United States among adults over 65 years old. [5] Not only is this the leading cause of hospitalization, it also increases the stays in the ICU. [ 21 ]
Nitroprusside or phenylephrine may be used in those with decompensated heart failure depending on the blood pressure. [1] [3] Aortic stenosis is the most common valvular heart disease in the developed world. [4] It affects about 2% of people who are over 65 years of age. [1] Estimated rates were not known in most of the developing world as of ...
In addition, hypertension precedes heart failure in 90% of cases, [7] and the majority of heart failure in the elderly may be attributable to hypertension. [17] Hypertensive heart disease was estimated to be responsible for 1.0 million deaths worldwide in 2004 (or approximately 1.7% of all deaths globally), and was ranked 13th in the leading ...
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