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Chromonychia can be induced by antineoplastic drugs with few distinct forms, the most frequently seen is melanonychia. [2] Although a few cytostatics may cause these changes, the drugs most commonly involved are adriamycin, cyclophosphamide and vincristine, or in polychemotherapy [3] [4] Also chromonychia is associated with AIDS.
Onychodystrophy is a deformation of the nails that can result from cancer chemotherapy which includes bleomycin, hydroxyurea, or 5-fluorouracil. It can include discoloration of the nail, or dyschromia. Onychogryposis, also called "ram's-horn nail", is a thickening and increase in curvature of the nail. It is usually the result of injury to the ...
CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Pale white nails If your fingernail beds are looking a little ghostly, you may have anemia due to low levels of iron. This could lead to low levels of oxygen, which causes the skin and tissues to ...
However, decreased circulation to fingertips, stripping nails with solvents during manicures, tumors and certain dermatological conditions can also cause vertical ridges in nails, she says. Causes ...
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...
2. You buffed your nails too much. Just as moisture-laden nails can be prone to peeling and splitting, so can nails that are dried out from too much buffing, according to Dr. Peters.