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Thujone (/ ˈ θ uː dʒ oʊ n / ⓘ [2]) is a ketone and a monoterpene that occurs predominantly in two diastereomeric forms: (−)-α-thujone and (+)-β-thujone. [3] [4]Though it is best known as a chemical compound in the spirit absinthe, it is only present in trace amounts and is unlikely to be responsible for the spirit's purported stimulant and psychoactive effects.
Since 2007, absinthe has been sold in the U.S. with regulated levels of thujone, a compound found in wormwood, a primary ingredient of absinthe, that has been linked to seizures and hallucinations.
Thujone, once widely believed to be an active chemical in absinthe, is a GABA antagonist, and while it can produce muscle spasms in large doses, there is no direct evidence to suggest it causes hallucinations. [99] Past reports estimated thujone concentrations in absinthe as being up to 260 mg/kg. [107]
[28] (−)-α-Thujone by itself is a GABA A receptor antagonist that can cause convulsions and death when administered in large amounts to animals and humans. [29] However, there is only one case of documented toxicity of wormwood involving a 31-year-old man who drank 10 mL of steam-distilled volatile oil of wormwood, wrongly believing it was ...
Mugwort often contains the neurotoxin compound thujone, though this varies greatly by species and the environmental conditions where the plant is grown. [25] Toxicity to humans is believed to be weak, though some studies have linked high concentrations of thujone to seizures and an abortive effect. [ 26 ]
The result was not only a genuine, historically accurate product, but one that met all requirements of the U.S. Alcohol and Tobacco Tax and Trade Bureau, including a stipulation that any finished food or beverage should test less than 10ppm or 10 mg/kg for Thujone pursuant to 21 CFR 172.510, which is well under the 35 mg/kg content that is ...
Thujene (or α-thujene) is a natural organic compound classified as a monoterpene. [1] It is found in the essential oils of a variety of plants, and contributes pungency to the flavor of some herbs such as Summer savory.
Illegal: Illegal: Illegal: Illegal Italy Illegal except Peyote: Illegal except Peyote: Illegal except Peyote: Legal: Mescaline is listed under Table 1 of Italy's "Tabelle delle sostanze stupefacenti e psicotrope" making it illegal to purchase, transport or sell. However, psychoactive cacti (with the exception of peyote) can be legally purchased ...