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Some of the proteins in snake venom have very specific effects on various biological functions, including blood coagulation, blood pressure regulation, and transmission of nerve or muscle impulses. These venoms have been studied and developed for use as pharmacological or diagnostic tools, and even drugs. [2] [5]
The discovery of an orally inactive peptide from snake venom established the important role of angiotensin converting enzyme (ACE) inhibitors in regulating blood pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse effects of captopril became apparent new
Venom-induced consumption coagulopathy (VICC) is a medical condition caused by the effects of some snake and caterpillar venoms on the blood. [1] Important coagulation factors are activated by the specific serine proteases in the venom and as they become exhausted, coagulopathy develops. Symptoms are consistent with uncontrolled bleeding.
Convulxin is a snake venom toxin found in a tropical rattlesnake known as Crotalus durissus terrificus. It belongs to the family of hemotoxins, which destroy red blood cells or, as is the case with convulxin, induce blood coagulation. [citation needed]
The earliest known use of venom in medicine dates back to 380 B.C. in ancient Greece. [5] Aristotle's "Historia Animalium", describes how venom can be used in the production of antidotes for the venom. [5] During the height of the Roman empire, there is evidence of venom being added into medicine used to treat smallpox, leprosy, fever, and ...
In addition to killing the prey, part of the function of a haemotoxic venom for some animals is to aid digestion. The venom breaks down protein in the region of the bite, making prey easier to digest. The process by which a haemotoxin causes death is much slower than that of a neurotoxin. Snakes which envenomate a prey animal may have to track ...
Snake antivenom is a medication made up of antibodies used to treat snake bites by venomous snakes. [1] It is a type of antivenom . It is a biological product that typically consists of venom neutralizing antibodies derived from a host animal, such as a horse or sheep.
α-Bungarotoxin is one of the bungarotoxins, components of the venom of the elapid Taiwanese banded krait snake (Bungarus multicinctus).It is a type of α-neurotoxin, a neurotoxic protein that is known to bind competitively and in a relatively irreversible manner to the nicotinic acetylcholine receptor found at the neuromuscular junction, causing paralysis, respiratory failure, and death in ...