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Bacteria exhibit three different types of asymmetry: conditional asymmetry, reproductive asymmetry, and morphological asymmetry. [2] Conditional asymmetry is well defined in the case of endospore formation, which is triggered by stressful environmental conditions such as increased heat, pH change, and nutrient depletion.
A well-studied example of pattern formation by asymmetric divisions is body axis patterning in Drosophila. RNA molecules are an important type of intracellular differentiation control signal. The molecular and genetic basis of asymmetric cell divisions has also been studied in green algae of the genus Volvox , a model system for studying how ...
An asymmetric cell division produces two daughter cells with different cellular fates. This is in contrast to symmetric cell divisions which give rise to daughter cells of equivalent fates. Notably, stem cells divide asymmetrically to give rise to two distinct daughter cells: one copy of the original stem cell as well as a second daughter ...
Furthermore, cell polarity is important during many types of asymmetric cell division to set up functional asymmetries between daughter cells. Many of the key molecular players implicated in cell polarity are well conserved. For example, in metazoan cells, the PAR-3/PAR-6/aPKC complex plays a fundamental role in cell polarity. While the ...
Nonrandom X-inactivation leads to skewed X-inactivation. Nonrandom X-inactivation can be caused by chance or directed by genes. If the initial pool of cells in which X-inactivation occurs is small, chance can cause skewing to occur in some individuals by causing a bigger proportion of the initial cell pool to inactivate one X chromosome.
The first one describes a bias and an asymmetric mutational pressure on each DNA strand during replication and transcription. [4] [11] Due to the asymmetric nature of the replication process, an unequal mutational frequency and DNA repair efficiency during the replication process can introduce more mutations in one strand as compared to the ...
Genetic erosion in agricultural and livestock is the loss of biological genetic diversity – including the loss of individual genes, and the loss of particular recombinants of genes (or gene complexes) – such as those manifested in locally adapted landraces of domesticated animals or plants that have become adapted to the natural environment in which they originated.
Fluctuating asymmetry (FA) is often considered to be the product of developmental stress and instability, caused by both genetic and environmental stressors. The notion that FA is a result of genetic and environmental factors is supported by Waddington's notion of canalisation, which implies that FA is a measure of the genome's ability to successfully buffer development to achieve a normal ...