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  2. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    In immunology, clonal selection theory explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body. The concept was introduced by Australian doctor Frank Macfarlane Burnet in 1957, in an attempt to explain the great diversity of antibodies formed during initiation of the immune response .

  3. Clonal selection algorithm - Wikipedia

    en.wikipedia.org/wiki/Clonal_Selection_Algorithm

    Clonal Selection Pseudo code on AISWeb; CLONALG in Matlab developed by Leandro de Castro and Fernando Von Zuben; Optimization Algorithm Toolkit in Java developed by Jason Brownlee which includes the following clonal selection algorithms: Adaptive Clonal Selection (ACS), Optimization Immune Algorithm (opt-IMMALG), Optimization Immune Algorithm (opt-IA), Clonal Selection Algorithm (CLONALG ...

  4. Clonal deletion - Wikipedia

    en.wikipedia.org/wiki/Clonal_deletion

    In immunology, clonal deletion is the process of removing T and B lymphocytes from the immune system repertoire. [ 1 ] [ 2 ] The process of clonal deletion helps prevent recognition and destruction of the self host cells, making it a type of negative selection .

  5. Affinity maturation - Wikipedia

    en.wikipedia.org/wiki/Affinity_maturation

    In immunology, affinity maturation is the process by which T FH cell-activated B cells produce antibodies with increased affinity for antigen during the course of an immune response. With repeated exposures to the same antigen, a host will produce antibodies of successively greater affinities .

  6. Clonal anergy - Wikipedia

    en.wikipedia.org/wiki/Clonal_anergy

    This process – called "clonal expansion" – allows the body to quickly mobilise an army of clones, as and when required. Such immune response is anticipatory and its specificity is assured by pre-existing clones of lymphocytes, which expand in response to specific antigen (process called "clonal selection").

  7. Clone (cell biology) - Wikipedia

    en.wikipedia.org/wiki/Clone_(cell_biology)

    Clonal expansion and monoclonal versus polyclonal proliferation. A clone is a group of identical cells that share a common ancestry, meaning they are derived from the same cell. [1] Clonality implies the state of a cell or a substance being derived from one source or the other.