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Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E) [5] – is a protein that in humans is encoded by the IL25 gene on chromosome 14. [ 6 ] [ 7 ] [ 8 ] IL-25 was discovered in 2001 and is made up of 177 amino acids.
Among IL-17 family members, the IL-17F isoforms 1 and 2 (ML-1) have the highest sequence homology with IL-17A (55 and 40%, respectively). They follow by IL-17B, which has 29% similarity to IL-17A, IL-17D (25%), IL-17C (23%), and IL-17E (17%). In mammals, the sequences of these cytokines are highly conserved. For instance, the sequence homology ...
IL-17RB binds preferentially IL-17B and IL-17E [4] [5] and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member IL-17RA is located on human chromosome 22, whereas other subunits IL-17RB to IL-17RD are encoded within human chromosome 3.
Adding a scoop of protein powder to your morning smoothie or drinking a protein shake post-workout isn’t guaranteed to cause weight gain. But there is a reason gym bros adore the stuff — it ...
3605 16171 Ensembl ENSG00000112115 ENSMUSG00000025929 UniProt Q16552 Q62386 RefSeq (mRNA) NM_002190 NM_010552 RefSeq (protein) NP_002181 NP_034682 Location (UCSC) Chr 6: 52.19 – 52.19 Mb Chr 1: 20.8 – 20.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-17A is a protein that in humans is encoded by the IL17A gene. In rodents, IL-17A used to be referred to as CTLA8 ...
50905 Ensembl ENSG00000056736 ENSMUSG00000015966 UniProt Q9NRM6 Q9JIP3 RefSeq (mRNA) NM_018725 NM_172234 NM_019583 RefSeq (protein) NP_061195 NP_062529 Location (UCSC) Chr 3: 53.85 – 53.87 Mb Chr 14: 29.72 – 29.73 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-17 receptor B is a protein that in humans is encoded by the IL17RB gene. The protein encoded by this gene is ...