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Eye development is initiated by the master control gene PAX6, a homeobox gene with known homologues in humans (aniridia), mice (small eye), and Drosophila (eyeless). The PAX6 gene locus is a transcription factor for the various genes and growth factors involved in eye formation. [1] [5] Eye morphogenesis begins with the evagination, or ...
During embryonic development of the eye, the outer wall of the bulb of the optic vesicles becomes thickened and invaginated, and the bulb is thus converted into a cup, the optic cup (or ophthalmic cup), consisting of two strata of cells.
The puzzle of how embryonic development was controlled began to be solved using the fruit fly Drosophila melanogaster as a model organism. The step-by-step control of its embryogenesis was visualized by attaching fluorescent dyes of different colours to specific types of protein made by genes expressed in the embryo. [9]
Human embryonic development covers the first eight weeks of development, which have 23 stages, called Carnegie stages. At the beginning of the ninth week, the embryo is termed a fetus (spelled "foetus" in British English). In comparison to the embryo, the fetus has more recognizable external features and a more complete set of developing organs.
Biological determinism, also known as genetic determinism, [1] is the belief that human behaviour is directly controlled by an individual's genes or some component of their physiology, generally at the expense of the role of the environment, whether in embryonic development or in learning. [2]
[18] [19] [20] Such high-level genes are, by implication, much older than many of the structures that they control today; they must originally have served a different purpose, before they were co-opted for eye development. [15] Eyes and other sensory organs probably evolved before the brain: There is no need for an information-processing organ ...
The development of plants involves similar processes to that of animals. However, plant cells are mostly immotile so morphogenesis is achieved by differential growth, without cell movements. Also, the inductive signals and the genes involved are different from those that control animal development.
The sclera, [note 1] also known as the white of the eye or, in older literature, as the tunica albuginea oculi, is the opaque, fibrous, protective outer layer of the eye containing mainly collagen and some crucial elastic fiber. [2] In the development of the embryo, the sclera is derived from the neural crest. [3]