Search results
Results From The WOW.Com Content Network
Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. [3] Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. [4]
Furthermore, multinucleated large cells with radically positioned nuclei in a "floret-like" pattern are strewn among the spindle cells. The histological spectrum is rather diverse, ranging from a tumor that primarily consists of spindle cells with only a few fat cells to a tumor that resembles an average lipoma with few spindle cells ...
The cells have large cytoplasmic lipid droplets interspersed throughout. [4] [5] Myxoid variant: Loose, basophilic matrix, with thick fibrous septa, and foamy histiocytes; Lipoma-like variant: Univacuolated lipocytes, with only isolated hibernoma cells; Spindle cell variant: Spindle cell lipoma combined with hibernoma
Microscopy of tumors in the spindle cell lipoma tentative variant of MFB show a mixture of mature fat cells, ropey collagen, and spindle cells in a myxoid (i.e. background connective tissue that stains blue or purple rather than the red of normal connective tissue) matrix. [18] The blood vessels in these tumors often appear hyalinized. [16]
Cellular angiofibroma (CAF) is a rare, benign tumor of superficial soft tissues that was first described by M. R. Nucci et al. in 1997. [1] These tumors occur predominantly in the distal parts of the female and male reproductive systems, i.e. in the vulva-vaginal and inguinal-scrotal areas, respectively, or, less commonly, in various other superficial soft tissue areas throughout the body. [2]
In neurobiology, spindle cell refers to: Spindle neuron, also known as a von Economo neuron; In general medicine, a spindle cell may refer to the spindle-shaped cells that are found in certain types of tumor: Inflammatory fibroid polyp; Pigmented spindle cell nevus; Spindle cell carcinoma; Spindle cell lipoma; Spindle cell sarcoma
Atypical fibroxanthoma (AFX) is frequently found to have a well-circumscribed, nonencapsulated dermal tumor that is either contiguous with the epidermis or separated from it by a narrow zone of collagen (Grenz zone); plump spindle cells with prominent nuclei, epithelioid cells, and multinucleated giant cells; atypical mitoses and severe ...
The presence of eccrine sweat glands are used to distinguish the tumor from a common lipoma. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis.