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Elias James Corey (born July 12, 1928) is an American organic chemist. In 1990, he won the Nobel Prize in Chemistry "for his development of the theory and methodology of organic synthesis ", [ 3 ] specifically retrosynthetic analysis .
Medical biochemistry [102] [103] Elias James Corey: University of Illinois: New synthetic methods based on biosynthetic principles: Also won in 1968 [63] [62] [3] Frank Albert Cotton: Massachusetts Institute of Technology: Chemistry of metal derivatives of cyclopentadiene: Also won in 1989 [23] [3] Walter Francis Richard Edgell: Purdue University
Elias James Corey, organic chemist, emeritus professor of organic chemistry at Harvard University, recipient of the Nobel Prize in Chemistry in 1990 [279] Ruth Schwartz Cowan, historian of science, technology, and medicine, Professor Emerita at the University of Pennsylvania [10]
The first total syntheses of prostaglandin F 2α and prostaglandin E 2 were reported by Elias James Corey in 1969, [9] an achievement for which he was awarded the Japan Prize in 1989. In 1971, it was determined that aspirin -like drugs could inhibit the synthesis of prostaglandins.
The Corey–Seebach reaction, or Seebach Umpolung is a name reaction of organic chemistry that allows for acylation by converting aldehydes into lithiated 1,3-dithianes. The lithiated 1,3-dithianes serves as an acyl anion equivalent, undergoing alkylation with electrophiles . [ 1 ]
Biophysical chemistry is a physical science that uses the concepts of physics and physical chemistry for the study of biological systems. [1] The most common feature of the research in this subject is to seek an explanation of the various phenomena in biological systems in terms of either the molecules that make up the system or the supra-molecular structure of these systems. [2]
Bioorganic chemistry is a scientific discipline that combines organic chemistry and biochemistry. It is that branch of life science that deals with the study of biological processes using chemical methods. [1] Protein and enzyme function are examples of these processes. [2]
The Corey–House synthesis (also called the Corey–Posner–Whitesides–House reaction and other permutations) is an organic reaction that involves the reaction of a lithium diorganylcuprate with an organic halide or pseudohalide (′) to form a new alkane, as well as an ill-defined organocopper species and lithium (pseudo)halide as byproducts.