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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [ 2 ] [ 3 ] [ 4 ] Salts of this anion, especially docusate sodium , are widely used in medicine as an emollient laxative and as stool softeners , by mouth or rectally. [ 1 ]
Simple English; Slovenčina; ... Examples: Docusate (Colace, Diocto), Gibs-Eze [3] Emollient agents prevent constipation rather than treating long-term constipation. [3]
Co-danthrusate is a combination of dantron and docusate. Dantron is a mild peristaltic stimulant which acts on the lower bowel to encourage normal bowel movement without causing irritation. It belongs to the group of medicines under the term stimulant laxative . [ 1 ]
[9] [10] In 2022, the combination with docusate was the 261st most commonly prescribed medication in the United States, with more than 1 million prescriptions. [9] [11] It is sold under a number of brand names including Ex-Lax and Senokot. [1]
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Hugo Colace (disambiguation), several people The Bella Twins (born 1983), the Garcia Colace twin sister pro-wrestlers . Brie Bella (born 1983, as Brianna Monique Garcia Colace) twin pro-wrestler
A high volume example is sodium bis(2-ethylhexyl) sulfosuccinate. This is perhaps best known as the laxative docusate, however its main use is as a surfactant for which it finds common use in personal-care and household-care products, often under the name Aerosol-OTs. [1]
It is a key intermediate raw material in the production of dioctyl sulfosuccinate (DOSS, docusate) salts, used medically as laxatives and stool softeners, and in many other applications as versatile surfactants. [2] [3] [4]