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Elias James Corey (born July 12, 1928) is an American organic chemist. In 1990, he won the Nobel Prize in Chemistry "for his development of the theory and methodology of organic synthesis ", [ 3 ] specifically retrosynthetic analysis .
The first total syntheses of prostaglandin F 2α and prostaglandin E 2 were reported by Elias James Corey in 1969, [9] an achievement for which he was awarded the Japan Prize in 1989. In 1971, it was determined that aspirin -like drugs could inhibit the synthesis of prostaglandins.
Jason Altom (6 October 1971 – 15 August 1998) was an American PhD student working in the research group of Nobel laureate Elias James Corey at Harvard University. He killed himself by taking potassium cyanide in 1998, citing in his suicide note "abusive research supervisors" as one reason for taking his life. Altom was studying a complex ...
The Corey–Seebach reaction, or Seebach Umpolung is a name reaction of organic chemistry that allows for acylation by converting aldehydes into lithiated 1,3-dithianes. The lithiated 1,3-dithianes serves as an acyl anion equivalent, undergoing alkylation with electrophiles . [ 1 ]
The Corey–House synthesis (also called the Corey–Posner–Whitesides–House reaction and other permutations) is an organic reaction that involves the reaction of a lithium diorganylcuprate with an organic halide or pseudohalide (′) to form a new alkane, as well as an ill-defined organocopper species and lithium (pseudo)halide as byproducts.
Textbook of Biochemistry is divided into the following chapters: [2] Introduction; Introduction to the concept of biochemistry, and a review of catalytic reactions and pH. Food-Stuffs, Their Derivatives and Related Substances. Ideas regarding carbohydrates, lipids, and proteins. The Chemistry of Digestion, the Circulation, and the Excreto.
In biochemistry, the Corey-Pauling rules are a set of three basic statements that govern the secondary nature of proteins, in particular, the CO-NH peptide link. They were originally proposed by Robert Corey and Linus Pauling. [1] The rules are as follows: The atoms in a peptide link all lie on the same plane.
Testing Ames test – salmonella bacteria is exposed to a chemical under question (a food additive, for example), and changes in the way the bacteria grows are measured.. This test is useful for screening chemicals to see if they mutate the structure of DNA and by extension identifying their potential to cause cancer in hu