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  2. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Similar to other antimetabolite anti-cancer drugs, it acts by disrupting the DNA replication process of dividing cancer cells in the body. Hydroxyurea selectively inhibits ribonucleoside diphosphate reductase , an enzyme required to convert ribonucleoside diphosphates into deoxyribonucleoside diphosphates, thereby preventing cells from leaving ...

  3. Gemcitabine - Wikipedia

    en.wikipedia.org/wiki/Gemcitabine

    Gemcitabine, sold under the brand name Gemzar, among others, [1] is a chemotherapy medication used to treat cancers. [2] It is used to treat testicular cancer, [3] breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer.

  4. CHOP (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/CHOP_(chemotherapy)

    Normal cells are more able than cancer cells to repair damage from chemotherapy drugs. This regimen can also be combined with the monoclonal antibody rituximab if the lymphoma is of B cell origin; this combination is called R-CHOP.

  5. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage.

  6. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    Drugs used in chemotherapy can induce cell stress, which can kill a cancer cell; however, under certain conditions, cells stress can induce changes in gene expression that enables resistance to several types of drugs. [147] In lung cancer, the transcription factor NFκB is thought to play a role in resistance to chemotherapy, via inflammatory ...

  7. Doxorubicin - Wikipedia

    en.wikipedia.org/wiki/Doxorubicin

    Doxorubicin hydrochloride (as Myocet liposomal) is indicated to treat breast cancer in combination with cyclophosphamide. [ 2 ] Doxorubicin is commonly used to treat some leukemias and lymphomas , as well as cancers of the bladder , breast , stomach , lung , ovaries , thyroid , soft tissue sarcoma as well as aggressive fibromatosis (desmoid ...

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