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When these enzymes are produced in low quantities, lactase non-persistence (LNP) results. [38] The ability to digest fresh milk through adulthood is genetically coded for by different variants which are located upstream of the LCT gene and which differ among populations. Those variants are found at very high frequencies in some populations and ...
However, most people worldwide remain lactase non-persistent. [9] Populations that raised animals not used for milk tend to have 90–100 percent of a lactose intolerant rate. [80] For this reason, lactase persistence is of some interest to the fields of anthropology, human genetics, and archaeology, which typically use the genetically derived ...
Lactase (EC 3.2.1.108) is an enzyme produced by many organisms and is essential to the complete digestion of whole milk.It breaks down the sugar lactose into its component parts, galactose and glucose.
The majority of humans actually follow this protocol as well, and down-regulate lactase production around 3-5 years of age. Interestingly, though, the majority of caucasians, mainly those from northern european background, continue to have elevated lactase activity all the way into adulthood, and so they exhibit “lactase persistence”.
The MCM complex consisting of MCM6 (this protein) and MCM2, 4 and 7 possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.
Lactose synthase is an enzyme that generates lactose from glucose and UDP-galactose.. It is classified under EC 2.4.1.22.. It consists of N-acetyllactosamine synthase and alpha-lactalbumin.
The lactase persistence example may be representative of a very general pattern of gene-culture coevolution. Niche construction is also now central to several accounts of how language evolved. For instance, Derek Bickerton describes how our ancestors constructed scavenging niches that required them to communicate in order to recruit sufficient ...
Diploid organisms (e.g., humans) contain two copies of each gene—a paternal and a maternal allele. Based on the occurrence of mutation on each chromosome, we may classify mutations into three types. A wild type or homozygous non-mutated organism is one in which neither allele is mutated. A heterozygous mutation is a mutation of only one allele.