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  2. Title 21 CFR Part 11 - Wikipedia

    en.wikipedia.org/wiki/Title_21_CFR_Part_11

    FDA had previously announced that a new Part 11 would be released late 2006. The Agency has since pushed that release date back. The FDA has not announced a revised time of release. John Murray, member of the Part 11 Working Group (the team at FDA developing the new Part 11), has publicly stated that the timetable for release is "flexible".

  3. Computerized system validation - Wikipedia

    en.wikipedia.org/wiki/Computerized_system_validation

    The system lifecycle then enters the operational phase and continues until system retirement and retention of system data based on regulatory rules. Similarly, The Rules Governing Medicinal Products in the European Union, Volume 4, Annex 11: Computerised Systems applies to all forms of computerized systems used as part of a GMP regulated ...

  4. Continued process verification - Wikipedia

    en.wikipedia.org/wiki/Continued_process_verification

    An alert system to identify process malfunctions that lead to deviations from quality standards. A framework for gathering and analyzing data of final product quality and process consistency. Analysis should include source materials consistency and manufacturing equipment condition; and data should be collected in a format that allows for long ...

  5. Validation (drug manufacture) - Wikipedia

    en.wikipedia.org/wiki/Validation_(drug_manufacture)

    The desired results are established in terms of specifications for outcome of the process. Qualification of systems and equipment is therefore a part of the process of validation. Validation is a requirement of food, drug and pharmaceutical regulating agencies such as the US FDA and their good manufacturing practices guidelines. Since a wide ...

  6. Trial master file - Wikipedia

    en.wikipedia.org/wiki/Trial_master_file

    It does not provide guidance on the process by which the content is created, managed or retained. TMF Reference Model shortcomings. As of May 2013, the TMF RM v2.0 was made available in an electronic spreadsheet format which is suitable for human viewing.

  7. Fast Healthcare Interoperability Resources - Wikipedia

    en.wikipedia.org/wiki/Fast_Healthcare...

    It is designed to be flexible and adaptable, so that it can be used in a wide range of settings and with different health care information systems. The standard describes data formats and elements (known as "resources") and an application programming interface (API) for exchanging electronic health records (EHR).

  8. Title 21 of the Code of Federal Regulations - Wikipedia

    en.wikipedia.org/wiki/Title_21_of_the_Code_of...

    Title 21 is the portion of the Code of Federal Regulations that governs food and drugs within the United States for the Food and Drug Administration (FDA), the Drug Enforcement Administration (DEA), and the Office of National Drug Control Policy (ONDCP). [1] It is divided into three chapters: Chapter I — Food and Drug Administration

  9. Standard for Exchange of Non-clinical Data - Wikipedia

    en.wikipedia.org/wiki/Standard_for_Exchange_of...

    This was soon followed by the FDA's statement of preference for SEND datasets. In December 2014, the FDA CDER and CBER divisions released guidance for industry enforcing the usage of SEND as part of Investigational New Drug (IND) and Biologic License Application (BLA) submission to the US Food and Drug Administration. All studies started after ...

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