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The management of patients with exacerbations of COPD is discussed here. A table to assist with emergency management of severe acute exacerbations of COPD is provided (table 1). The diagnosis and treatment of infection in exacerbations and the management of stable COPD are discussed separately.
Typical interventions used for the management of COPD exacerbations include corticosteroids, systemic antibiotics, inhaled bronchodilators, and supplemental oxygen.
ABG analysis should be used to detect respiratory failure in patients with COPD exacerbation, determine the indication for oxygen therapy, measure treatment response, and in the differential diagnosis of metabolic disturbances accompanying COPD exacerbations.
• COPD may be punctuated by periods of acute worsening of respiratory symptoms, called exacerbations. • In most patients, COPD is associated with significant concomitant chronic diseases, which increase
Physicians should consider antibiotics for patients with purulent sputum and for patients who have inadequate symptom relief with bronchodilators and corticosteroids. The choice of antibiotic...
Feemster LC, Pasnick SD, Weinstock T, Chatterjee RS, Krishnan JA, Miravitlles M, et al. Clinical practice guideline summary for clinicians: Management of COPD exacerbations: an ERS/ATS guideline. MOC Self-Assessment Module. Scientific Symposia.
Pharmacologic treatment for COPD aims to improve quality of life (QOL) and control symptoms while reducing the frequency of exacerbations. The purpose of this clinical practice guideline is to address specific clinically important questions regarding the pharmacologic management of COPD.
Most patients hospitalized with exacerbation of chronic obstructive pulmonary disease (COPD) require oxygen supplementation during an exacerbation. Inhaled short-acting beta-agonists are the cornerstone of medication therapy for acute exacerbations.
Most patients who are hospitalized with an exacerbation of COPD should be treated with systemic corticosteroids, unless side-effects are limiting [I, A]. A dose of prednisone, 40 mg orally daily, for a 5-day course, is appropriate for most patients, and a dose taper is unnecessary (Table 3) [I, A]. Antibiotics.
Key Recommendations. Systemic antibiotics should be prescribed for adults with acute exacerbations of COPD to improve clinical cure and reduce clinical failure. Choice of antibiotic should be...