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Atherosclerosis is the most common cause of stenosis (narrowing of the blood vessels) of the heart's arteries and, hence, angina pectoris. Some people with chest pain have normal or minimal narrowing of heart arteries; in these patients, vasospasm is a more likely cause for the pain, sometimes in the context of Prinzmetal's angina and syndrome X.
Reduced blood flow to the heart associated with coronary ischemia can result in inadequate oxygen supply to the heart muscle. [6] When oxygen supply to the heart is unable to keep up with oxygen demand from the muscle, the result is the characteristic symptoms of coronary ischemia, the most common of which is chest pain. [6]
All right, as a quick recap…. Angina pectoris is chest pain caused by reduced blood flow resulting in a lack of oxygen in the heart muscle. There are three types: stable angina, unstable angina, and vasospastic angina. Rest tends to relieve stable angina, but not the other two types, and all three can be treated with nitroglycerin.
Chest pain that gets worse when you inhale deeply is called "pleuritic pain," Martin explains. Pericarditis can cause pleuritic pain, but this type of discomfort is typically related to lung ...
Cardiac ischemia may be asymptomatic or may cause chest pain, known as angina pectoris. It occurs when the heart muscle, or myocardium , receives insufficient blood flow. [ 10 ] This most frequently results from atherosclerosis , which is the long-term accumulation of cholesterol-rich plaques in the coronary arteries .
Kamath says it can cause intermittent chest pain or sharp, tearing chest pain that often radiates to the shoulders and the back. It more often happens to men between the ages of 60 and 80.
The main reason for the acute phase of ischemia-reperfusion injury is oxygen deprivation and, therefore, arrest of generation of ATP (cellular energy currency) by mitochondria oxidative phosphorylation. Tissue damage due to the general energy deficit during ischemia is followed by reperfusion (increase of oxygen level) when the injury is enhanced.
The causes are unknown, but this kind of chest pain is often seen with arthritis, trauma to the chest wall (something heavy hitting your chest), bacterial infections, and excessive coughing from a ...