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Ovarian tumours by incidence and risk of ovarian cancer, with adult granulosa cell tumour at right [7] Using next generation DNA sequencing, 97% of adult granulosa cell tumours were found to contain an identical mutation in the FOXL2 gene . This is a somatic mutation, meaning it is not usually transmitted to descendants.
A very rare tumour producing both ovarian (granulosa and/or theca) and testicular (Sertoli and/or Leydig) cells or tissues. Typically it consists of adult-type granulosa cells and Sertoli cells, [4] [5] but it has been reported with juvenile-type granulosa cells. [6] It has been reported to occur in the ovary usually, rarely in the testis. [7]
Adult granulosa cell tumors are characterized by later onset (30+ years, 50 on average). These tumors produce high levels of estrogen, which causes its characteristic symptoms: menometrorrhagia; endometrial hyperplasia; tender, enlarged breasts; postmenopausal bleeding; and secondary amenorrhea.
In medicine, Meigs's syndrome, also Meigs syndrome or Demons–Meigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian tumor (ovarian fibroma, fibrothecoma, Brenner tumour, and occasionally granulosa cell tumour). [1] [2] [3] Meigs syndrome resolves after the resection of the tumor. Because the transdiaphragmatic lymphatic ...
Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue 40% of the time. It is also known as Abrikossoff's tumor , [ 1 ] granular cell myoblastoma , [ 1 ] granular cell nerve sheath tumor , [ 1 ] and granular cell schwannoma . [ 1 ]
1 Signs and symptoms. 2 Pathophysiology. 3 Diagnosis. 4 References. ... lined by one or more layers of granulosa cell, and filled with clear fluid. [citation needed]
A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called an oocyte or egg) in the ovary of mammals. Structure and function
A dysgerminoma is a type of germ cell tumor; [1] it usually is malignant and usually occurs in the ovary.. A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis [2] or germinoma in the central nervous system or other parts of the body.