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The Mayo Clinic states that there is no evidence that pharmacy-compounded BHT is safer or more effective than conventional hormone replacement, and that some bioidentical hormones are already available in certain FDA-approved products. [37]
Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. [12] [4] [6] [13] It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs.
[7] [5] [6] Estradiol acetate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [8] [9] It is an estrogen ester and a prodrug of estradiol in the body. [9] [8] Because of this, it is considered to be a natural and bioidentical form of estrogen. [9] [10]
Estradiol benzoate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [4] [5] It is an estrogen ester and a prodrug of estradiol in the body. [4] [5] Because of this, it is considered to be a natural and bioidentical form of estrogen. [4]
[14] [8] Estradiol cypionate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [8] [7] Estradiol cypionate is an estrogen ester and a long-lasting prodrug of estradiol in the body. [14] [8] [7] Because of this, it is considered to be a natural and bioidentical form of estrogen ...
[15] [13] [14] Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [5] [4] [16] It is an estrogen ester and a prodrug of estradiol in the body. [16] [5] [4] Because of this, it is considered to be a natural and bioidentical form of estrogen. [16] [17] [4] [18]
Estradiol is an estrogen, or an agonist of the estrogen receptors (ERs), the ERα Tooltip estrogen receptor alpha and ERβ Tooltip estrogen receptor beta. [11] It is also an agonist of membrane estrogen receptors (mERs), including the GPER Tooltip G protein-coupled estrogen receptor, G q-mER Tooltip Gq-coupled membrane estrogen receptor, ER-X ...
Xenoestrogens are xenohormones that mimic the effects of natural estrogen. When present in the body, xenoestrogens can bind with estrogen receptors in the brain, leading to a disruption in the gonadal endocrine system. Xenoestrogen exposure during different developmental periods can have differing effects on the reproductive system.