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Alois Alzheimer is often credited with first linking plaques to dementia in a 1906 presentation (published in 1907), [12] but this short report focused mainly on neurofibrillary tangles, and plaques were only briefly mentioned. [4] Alzheimer's first substantive description of plaques appeared in 1911. [11]
The American Journal of Alzheimer's Disease & Other Dementias is a peer-reviewed academic journal that publishes papers in the field of neurology. The journal's editor is Carol F. Lippa, MD (Drexel University College of Medicine). It has been in publication since 1986 and is currently published by SAGE Publications.
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. [2] It is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1]
Familial Alzheimer's disease mutations commonly used in animal models. Rodent animal models of Alzheimer's disease are commonly used in research as rodents and humans have many of the same major brain regions and neurotransmitter systems. [5] These models are small, easy to house, as well as breed very well. [26]
Since dementia patients have trouble communicating their needs, this can be frustrating for the nurse. Nurses may have a hard time forming relationships with their dementia patients because of the communication barrier. How the dementia patient feels is based on their social interactions, and they may feel neglected because of this barrier. [35]
Carol Joyce Jennings (née Bexon; 25 March 1954 – 29 March 2024) was a British campaigner and advocate for research into Alzheimer's disease.She served as an honorary Vice-President of the Alzheimer's Society until her death in 2024. [1]