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Sequence analysis. In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. It can be performed on the entire genome, transcriptome or proteome of an organism, and can also involve only selected ...
DNA sequencer. A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine). This is then reported as a text string, called a read.
DNA sequencing may be used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes, or entire genomes of any organism. DNA sequencing is also the most efficient way to indirectly sequence RNA or proteins (via their open reading frames).
Early bioinformatics—computational alignment of experimentally determined sequences of a class of related proteins; see § Sequence analysis for further information. Bioinformatics (/ ˌbaɪ.oʊˌɪnfərˈmætɪks / ⓘ) is an interdisciplinary field of science that develops methods and software tools for understanding biological data ...
DNAnexus is an American company that provides a cloud-based data analysis and management platform for DNA sequence data.It is based in Mountain View, California, and was founded in 2009 by Stanford University professors Serafim Batzoglou and Arend Sidow and Stanford computer scientist Andreas Sundquist.
Gene Codes Corporation was founded in 1988 in Ann Arbor, Michigan. In 1991, the DNA sequence assembly and analysis software, Sequencher, was released. By 1997, nearly every major pharmaceutical company and commercial genomics company in the world was standardized on Sequencher, as well as the majority of labs at major academic centers.
EMBOSS. EMBOSS is a free c software analysis package developed for the needs of the molecular biology and bioinformatics user community. [1] The software automatically copes with data in a variety of formats and even allows transparent retrieval of sequence data from the web. Also, as extensive libraries are provided with the package, it is a ...
ChIP sequencing. ChIP-sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins. It can be used to map global binding sites precisely for any protein of interest.