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Many diseases cause sweat gland dysfunction: Acromegaly, a result of excess growth hormone, causes the size of sweat glands increase, which leads to thicker skin. [71] Aquagenic wrinkling of the palms, in which white papules develop on the palms after exposure to water, can sometimes come with abnormal aquaporin 5 in the sweat glands. [72]
Perspiration, also known as sweat, is the fluid secreted by sweat glands in the skin of mammals. [ 1 ] Two types of sweat glands can be found in humans: eccrine glands and apocrine glands . [ 2 ]
Hands, feet, armpits, groin, and the facial area are among the most active regions of perspiration due to the high number of sweat glands (eccrine glands in particular) in these areas. When excessive sweating is localized (e.g. palms, soles, face, underarms, scalp) it is referred to as primary hyperhidrosis or focal hyperhidrosis.
Hyperhidrosis is the medical term for excessive sweating in the underarms, face, scalp, palms and feet, according to Johns Hopkins Medicine, which also notes that people experiencing it often ...
The common condition is defined as when the sweat glands and ducts get blocked, leading to the sweat to flow back into the outer (epidermis) and middle (dermis) layers of skin.
Focal hyperhidrosis, also known as primary hyperhidrosis, is a disease characterized by an excessive sweating localized in certain body regions (particularly palms, feet and underarms). Studies suggest that this condition, affecting between 1% and 3% of the US population, seems to have a genetic predisposition in about two thirds of those affected.
Eccrine sweat glands are found in virtually all skin, with the highest density in the palms of the hands, and soles of the feet, and on the head, but much less on the torso and the extremities. In other mammals, they are relatively sparse, being found mainly on hairless areas such as foot pads.
Cold sweats most often appear on your palms, armpits, and the soles of your feet. “Cold sweat symptoms usually include fatigue, chills, and swollen lymph nodes,” Dr. Salzberg says.