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Other infections include neonatal sepsis, where the immune system reacts by affecting their organs and tissues resulting in meningitis, seizures, and cerebral palsy. [30] The mother's health is also associated with perinatal stroke, some factors include blood clotting disorders, congenital heart diseases, and prenatal cocaine exposure. [31]
This is associated with cerebral palsy and is suggestive of a hypercoagulable state as the underlying cause. Cerebral palsy is due to abnormal development or damage occurring to the developing brain. [72] This damage can occur during pregnancy, delivery, the first month of life, or less commonly in early childhood. [72]
Despite the varying grades of PVL and cerebral palsy, affected infants typically begin to exhibit signs of cerebral palsy in a predictable manner. Typically, some abnormal neurological signs (such as those previously mentioned) are visible by the third trimester of pregnancy (28 to 40 weeks after conception), and definitive signs of cerebral ...
Neonatal stroke, similar to a stroke which occurs in adults, is defined as a disturbance to the blood supply of the developing brain in the first 28 days of life. [1] This description includes both ischemic events, which results from a blockage of vessels, and hypoxic events, which results from a lack of oxygen to the brain tissue, as well as some combination of the two.
Neurological problems can include apnea of prematurity, hypoxic-ischemic encephalopathy (HIE), retinopathy of prematurity (ROP), [186] developmental disability, transient hyperammonemia, cerebral palsy, and intraventricular hemorrhage, the latter affecting 25% of babies born preterm, usually before 32 weeks of pregnancy. [187]
“After 30 minutes, seizures cause brain damage. So he was likely getting one week’s worth of brain damage already out of the gate. And it’s possible that he was having seizures in utero and ...
Fetal alcohol spectrum disorders are a group of conditions caused prior to birth that can occur in a person whose mother drank alcohol during pregnancy. Cerebral palsy is a group of disorders that affect a person's ability to move and maintain balance and posture. They are the most common motor disability in childhood.
Damage to the developing oligodendrocytes near the cerebral ventricles causes cerebral palsy as well as other demyelinating diseases such as multiple sclerosis and leukodystrophies. Demyelination reduces the speed of conduction in affected nerves resulting in disabilities in cognition, sensation, and motor.