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Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]
Triple-negative breast cancer (up to 15% of cases) and inflammatory breast cancer (up to 5% of cases) are particularly aggressive and have relatively poor prognoses. [ 87 ] [ 88 ] Those with triple-negative breast cancer have an overall five-year survival rate of 77% – 91% for those whose tumors are confined to the breast; 12% for those with ...
Conversely, triple negative cancer (i.e. no positive receptors), lacking targeted treatments, now has a comparatively poor prognosis. [42] [43] Androgen receptor is expressed in 80-90% of ER+ breast cancers and 40% of "triple negative" breast cancers. Activation of androgen receptors appears to suppress breast cancer growth in ER+ cancer while ...
Mackey's “first ever mammogram,” led to a biopsy that diagnosed her with stage 3 triple negative breast cancer. The mom of two daughters, 3 and 6 at the time, felt ready to act.
Adu tells Yahoo Life that she was diagnosed with stage III, grade 3, triple-negative breast cancer in 2020 when she was 35. "The cancer had already spread to my lymph nodes, but knowing my body ...
Breast cancer is the most common cancer in women worldwide, and can, rarely, also occur in men. There are many different types of breast cancer, of which triple-negative breast cancer is one of ...
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