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The ability to invade surrounding tissue and metastasise is a hallmark of cancer. The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities. The idea was coined by Douglas Hanahan and Robert ...
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Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [11] CA-125: Mainly ovarian cancer, [12] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [13] Calcitonin: medullary thyroid carcinoma [14] Calretinin
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Craig Shergold (24 June 1979 – 21 April 2020) was a British cancer patient who received an estimated 350 million greeting cards, earning him a place in the Guinness Book of World Records. Variations of the plea for greeting cards on his behalf in 1989 are still being distributed through the Internet, making the plea one of the most persistent ...
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With Robert Weinberg, he wrote a seminal paper The Hallmarks of Cancer, published in January 2000, and which in March 2011 is the most cited article from the peer reviewed journal Cell. [5] In 2011, they published an updated review article entitled "Hallmarks of cancer: the next generation". [6]
The zebra has been used as a symbol for rare diseases since around 1940. Dr. Theodore Woodward, a professor at the University of Maryland's School of Medicine [1] used this term to teach students the basics of diagnosing disease: "When looking at a patient's symptoms, it is better to assume it is a common ailment, not a rare one – a horse rather than a zebra."