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Methenamine is used in the treatment and prevention of recurrent urinary tract infections (UTIs) requiring long-term therapy. [3] [1] [2] It is approved and used in both adults and children at least 6 years of age.
Methenamine serves as a urinary antiseptic and antibacterial agent, while sodium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic. The combination is used for the treatment and prevention of urinary tract infection (UTI) symptoms. [1] [2] [3] [4]
[4] [10] [11] [12] It is used as an alternative to antibiotics to prevent urinary tract infections (UTIs) and is sold under the brand names Hiprex, Urex, and Urotropin, among others. [4] [10] [12] As the mandelic acid salt (methenamine mandelate) or the hippuric acid salt (methenamine hippurate), [13] it is used for the treatment of urinary ...
TMP/SMX is commonly used due to its ability to achieve high concentrations in urinary tract tissues and urine. This antibiotic combination demonstrates notable efficacy in both the treatment and prophylaxis of recurrent urinary tract infections. [12] Common adverse effects include nausea, vomiting, rash,pruritus, and photosensitivity. [26]
A urinary tract infection ... As methenamine is an antiseptic, it may avoid the issue of antibiotic resistance. ... and treatment before urinary tract procedures ...
Methenamine is a urinary antiseptic and antibacterial agent which is used in the prevention of recurrent urinary tract infections (UTIs). [42] It is non-inferior to low-dose prophylactic antibiotics for this purpose. [43] [44] [45] In contrast however, methenamine itself is not an antibiotic and does not promote antibiotic resistance.