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  2. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    Drawing of sclerotic lesions from Babinski's thesis "Etude anatomique et clinique de la sclérose en plaques", 1885. Multiple sclerosis (MS) can be pathologically defined as the presence of distributed glial scars in the central nervous system that must show dissemination in time (DIT) and in space (DIS) to be considered MS lesions. [1] [2]

  3. Lesional demyelinations of the central nervous system

    en.wikipedia.org/wiki/Lesional_demyelinations_of...

    However, in a person with MS, these cells recognize healthy parts of the central nervous system as foreign and attack them as if they were an invading virus, triggering inflammatory processes and stimulating other immune cells and soluble factors like cytokines and antibodies. Many of the myelin-recognizing T cells belong to a terminally ...

  4. Template:Table of MRI sequences - Wikipedia

    en.wikipedia.org/wiki/Template:Table_of_MRI...

    High signal for paramagnetic substances, such as MRI contrast agents [2] Standard foundation and comparison for other sequences T2 weighted: T2: Measuring spin–spin relaxation by using long TR and TE times Higher signal for more water content [1] Low signal for fat in standard Spine Echo (SE), [1] though not with Fast Spin Echo/Turbo Spin ...

  5. Pathophysiology of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of...

    Currently it is unknown what the primary cause of MS is; if MS is a heterogeneous disease, the lesion development process would not be unique. In particular, some PPMS patients having a special clinical course named rapidly progressive multiple sclerosis could have a special genetic cause [ 47 ] and a different development process.

  6. Diagnosis of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Diagnosis_of_multiple_sclerosis

    Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]

  7. Tumefactive multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Tumefactive_multiple_sclerosis

    Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics for those of standard multiple sclerosis (MS). It is called tumefactive as the lesions are "tumor-like" and they mimic tumors clinically, radiologically and sometimes pathologically.

  8. Signs and symptoms of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Main symptoms of multiple sclerosis Symptoms and findings in multiple sclerosis. Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing (), visual ...

  9. Physics of magnetic resonance imaging - Wikipedia

    en.wikipedia.org/wiki/Physics_of_magnetic...

    Modern 3 Tesla clinical MRI scanner.. Magnetic resonance imaging (MRI) is a medical imaging technique mostly used in radiology and nuclear medicine in order to investigate the anatomy and physiology of the body, and to detect pathologies including tumors, inflammation, neurological conditions such as stroke, disorders of muscles and joints, and abnormalities in the heart and blood vessels ...

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