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A urethral bulking injection is one type of treatment for incontinence in women. Urethral bulking injections are considered by a clinician when the woman has urinary sphincter dysfunction, urethral hypermobility, persistent stress urinary incontinence after a urethral sling or urethropexy, or stress urinary incontinence in women who cannot undergo surgery due to other illnesses or conditions.
Urinary retention is a relatively uncommon presentation in young women. Fowler's syndrome primarily presents in women between menarche and menopause. The peak age of onset is 26 yrs. [5] It is seen in about one third of the women who experience urinary retention. The predominant complaint is the inability to urinate for a day or more with no ...
For most, the effect will last beyond the first three to six months of direct Botox effect and is most frequently a lifelong cure. [13] A small percentage of patients will require a subsequent injection of Botox for lasting results. [14] An alternative if the injection is unsuccessful is to undergo partial cricopharyngeal myotomy. [15]
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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
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Surgical treatment, under general anaesthesia, is either anal stretch (Lord's operation) or lateral sphincterotomy where the internal anal sphincter muscle is incised. Both operations aim to decrease sphincter spasming and thereby restore normal blood supply to the anal mucosa. Surgical operations involve a general or regional anaesthesia.
Weak pelvic floor muscles, intrinsic sphincter damage, or damage to the surrounding nerves and tissue can make the urethral sphincter incompetent, and subsequently it will not close fully, leading to stress urinary incontinence. In women, childbirth, obesity, and age can all be risk factors, especially by weakening the pelvic floor muscles. [6]