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Unwanted weight loss of more than 5% within 6 months. [2] [19] For people with a BMI of less than 20kg/m 2, weight loss of more than 2%. [2] [19] [27] For people with sarcopenia, weight loss of more than 2%. [2] [19] [27] New ways to score and stage cachexia are being explored, particularly in people with advanced cancer. [19]
Cancers to suspect in patients with unexplained weight loss include gastrointestinal, prostate, hepatobiliary (hepatocellular carcinoma, pancreatic cancer), ovarian, hematologic or lung malignancies. People with HIV often experience weight loss, and it is associated with poorer outcomes. [62] Wasting syndrome is an AIDS-defining condition. [62]
Obesity has been associated with an increased risk of esophageal cancer, pancreatic cancer, colorectal cancer, breast cancer (among postmenopausal women), endometrial cancer, kidney cancer, thyroid cancer, liver cancer and gallbladder cancer. [2] Obesity may also lead to increased cancer-related mortality. [1]
Unintentional weight loss is always a concerning symptom and could be associated with different types of cancers, so it’s important to bring it up with your physician, Chung says.
Experts say that recent, unexplained weight loss is a "well-known phenomenon" associated with cancer. But other health conditions can cause weight loss as well.
Tamara Loving's mother died of cancer and she gained weight. After losing 122 pounds, she was so healthy that she did well with her own breast cancer journey. Woman says 100-pound weight loss ...
Unexplained weight loss: Weight loss that is unintended and not explained by diet, exercise or other illness may be a warning sign of many types of cancer; Unexplained pain: Pain that persists, has no clear cause, and does not respond to treatment may be a warning sign of many types of cancers.
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