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Pathological jaundice in newborns should be suspected when the serum bilirubin level rises by more than 5 mg/dL per day, serum bilirubin more than the physiological range, clinical jaundice more than 2 weeks, and conjugated bilirubin (dark urine staining clothes). Haemolytic jaundice is the commonest
Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [ 1 ]
Jaundice is commonly associated with severity of disease with an incidence of up to 40% of patients requiring intensive care in ICU experiencing jaundice. [48] The causes of jaundice in the intensive care setting is both due to jaundice as the primary reason for ICU stay or as a morbidity to an underlying disease (i.e. sepsis). [48]
Hemolytic jaundice, also known as prehepatic jaundice, is a type of jaundice arising from hemolysis or excessive destruction of red blood cells, ...
The 2014 Odisha hepatitis outbreak (initially known as the 2014 Sambalpur jaundice outbreak, in relation to the predominant symptom and location) was an outbreak of mainly Hepatitis E and also Hepatitis A which began in the town of Sambalpur in Odisha, India. [2]
Most (>95%) infants with biliary atresia will undergo an operation designed to retain and salvage the native liver, restore bile flow, and reduce the level of jaundice. This is known as the Kasai procedure (after Morio Kasai , the Japanese surgeon who first developed the technique) or hepatoportoenterostomy .
Jaundice in adults is associated with severity with up to 40% of individuals requiring intensive care experiencing jaundice either as the primary reason for ICU stay or associated with another high mortality disease process (i.e. sepsis). Also, persistence of jaundice (in general) is associated with greater morbidity and mortality.
Bilirubin (BR) (from the Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged or abnormal red blood cells. [3]