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The detection limit (according to IUPAC) is the smallest concentration, or the smallest absolute amount, of analyte that has a signal statistically significantly larger than the signal arising from the repeated measurements of a reagent blank. Mathematically, the analyte's signal at the detection limit is given by:
In measuring sensory threshold, noise must be accounted for. Signal noise is defined as the presence of extra, unwanted energy in the observational system which obscures the information of interest. As the measurements come closer to the absolute threshold, the variability of the noise increases, causing the threshold to be obscured. [5]
Detection theory or signal detection theory is a means to measure the ability to differentiate between information-bearing patterns (called stimulus in living organisms, signal in machines) and random patterns that distract from the information (called noise, consisting of background stimuli and random activity of the detection machine and of the nervous system of the operator).
In order for a stimulus to be detected with high probability, its level of strength must exceed the absolute threshold; if a signal does reach threshold, the information is transmitted to the central nervous system (CNS), where it is integrated and a decision on how to react is made. Although stimuli commonly cause the body to respond, it is ...
Under the influence of signal detection theory, absolute threshold has been redefined as the level at which a stimulus will be detected a specified percentage (often 50%) of the time. [1] The absolute threshold can be influenced by several different factors, such as the subject's motivations and expectations, cognitive processes, and whether ...
The detection scheme is similar to a radar-like "energy detection" because it includes signal squaring, temporal summation, and a threshold switch mechanism, just like the energy detector, but it also includes a unit that emphasizes stimulus edges and a variable memory length (variable memory).
If the fluorescent signal is weak, amplification of the signal may be necessary in order to exceed the detection threshold of the microscope. Fluorescent signal strength depends on many factors such as probe labeling efficiency, the type of probe, and the type of dye. Fluorescently tagged antibodies or streptavidin are bound to the dye molecule ...
In biology, quorum sensing or quorum signaling (QS) [1] is the process of cell-to-cell communication [2] that allows bacteria to detect and respond to cell population density by gene regulation, typically as a means of acclimating to environmental disadvantages.